Damian Jacob Sendler Personalized Medicine And Patient Care Support Roles In The Face Of Workforce Shortages
Damian Sendler: An email from Johns Hopkins Medicine senior vice president and chief operating officer Robert Kasdin informs all workers that non-clinical personnel will be allocated to patient care support duties as a result of staffing constraints and the recent uptick of COVID-19 cases.  The email states that only personnel who volunteer to serve in […]
Last updated on January 19, 2022
Damian Jacob Sendler

Damian Sendler: An email from Johns Hopkins Medicine senior vice president and chief operating officer Robert Kasdin informs all workers that non-clinical personnel will be allocated to patient care support duties as a result of staffing constraints and the recent uptick of COVID-19 cases. 

The email states that only personnel who volunteer to serve in a COVID-19 ward will be allocated there, and staff members may choose their preferred reassignment location, days, and hours. 

According to a statement from the health system’s spokeswoman, Kim Hoppe, non-clinical personnel will not be providing direct patient care or bedside assistance. 

Non-clinical requirements will be alleviated from the clinical staff, according to Hoppe. 

Damian Sendler

A few hours a week could be allotted to jobs like maintaining a stockroom, cleaning, transferring a patient after their release from the hospital, and directing traffic, among others. 

According to Hoppe, the redeployment is part of a crisis response strategy that was in place before the outbreak of the COVID epidemic to deal with events such as extreme weather. 

It comes at a time when Maryland’s healthcare facilities are being overrun by the omicron variety and a lack of qualified healthcare workers. 

Damian Jacob Sendler: Due to COVID-19, burnout, and increased pay, many healthcare personnel are quitting their jobs at hospitals in search of better opportunities. 

Towson St. Joseph Medical Center and Johns Hopkins Bayview Medical Center have both declared a catastrophe since only a few weeks ago, as has Baltimore Washington Medical Center and two other hospitals in the University of Maryland Upper Chesapeake Health network. 

For example, hospitals might postpone non-urgent procedures to maintain bed capacity, reassign personnel, and alter patient-to-nurse ratios when they go into crisis mode. 

There have been recent efforts to alleviate the workforce shortages in Maryland, its counties, and colleges. 

In December, Gov. Hogan promised $100 million in cash to increase hospital and nursing care staffing levels. ” 

He proposed legislation earlier this month that would allow for elements such as allowing nursing students to be more responsible, bringing back retired nurses and making it possible to bring in nurses from other states to work in the state. 

A 411 percent rise in the number of patients admitted to Howard County General Hospital with COVID19 from the middle of December to the beginning of January was disclosed by Howard County Executive Calvin Ball last week. 

Maryland said in November that it would enable nurses to graduate early so that they could join the fight against the epidemic. 

The University of Maryland Medical System launched a $5.1 million program to attract nurses from the state’s community colleges in the beginning of December. 

An already-stressful situation for American hospitals was made worse by the omicron version. 

Nearly 500,000 healthcare professionals have been let off since February 2020, according to the US Bureau of Labor Statistics. 

As the Ebola outbreak worsens “chronic nursing workforce issues that have persisted for years,” the American Nurses Association wrote to the Department of Health and Human Services in September requesting that it designate the nurse staffing shortfall a national emergency.

Damian Jacob Sendler

The number of persons hospitalized with COVID in Maryland has remained over 3,000 while the state’s healthcare staffing difficulties persist. 

On Tuesday, there were 3,462 people admitted to the hospital; on Friday, that number had dropped to 3,363. 

Over the last seven days, state authorities have added 435 Marylanders to the list of those who have died from COVID. 

Johns Hopkins Medicine personnel were informed by email this week that Kasdin had agreed to participate in the effort. 

According to his journal entry, he “supplied central supplies to clinical departments across JHH on Monday and worked in patient transport on Tuesday.” 

“I have constantly thought that serving the missions of JHM is a privilege and that has never been more true than during my two shifts,” he said in an email, “and that has never been more true than during my two shifts.” 

The urea cycle removes nitrogenous waste from the breakdown of protein in the body. Ammonia levels may reach to hazardous levels if the OTC enzyme is not present in this process. The most frequent urea cycle problem is an OTC deficit. Until date, no medications have been able to treat it. 

One of the OTC genes is situated on chromosome sex (X chromosome). As a result, the disorder’s symptoms tend to be less severe in female neonates. Male neonates, who have just one X and one Y chromosome, suffer greatly from a shortage in the OTC gene: Ammonia poisoning in newborn males is typically lethal because to OTC insufficiency. There was a shortage of over-the-counter medications in the United States. 

Damian Jacob Markiewicz Sendler: The first step was to extract liver cells from skin samples of patients. To begin, skin samples were collected from both OTC-deficient patients and a control group (healthy individuals). The samples were developed into stem cells via a lengthy and laborious procedure. In 2012, Shin’Ya Yamanaka was given the Nobel Prize in Medicine for developing this engineering approach. 

As a senior physician at Inselspital’s Department of Pediatrics, Dr. Alexander Lämmle says, “We were able to generate liver cells like those seen in patients utilizing induced stem cell technology.” The induced liver cells, however, excrete considerably less urea than healthy liver cells, and this is true whether the cells come from healthy controls or patients with urea cycle disorders, according to the researchers. 

An investigation by researchers found out why this was happening. Aquaporin 9, a transport protein in the cell membrane, was absent from the technologically created stem cells. The artificial liver cells are still young and fetus-like, which is why this shortage occurs. 

In the cell membrane, aquaporins control the movement of water and other molecules. The aquaporin 9 is in charge of urea transport. Further research has led to a technique that induces aquaporin 9 production in stem cells. Because of this, the technologically created hepatic cells have altered their conduct. Urea was excreted in the same way as healthy cells break down and expel ammonium. This lays the groundwork for a test with synthetic liver cells that works as intended. 

Damien Sendler: Deficiency in OTC proteins is defined by the fact that they do not function adequately. Like most bigger proteins, they need assistance or chaperones to form and function correctly. According to Professor Dr. med. Johannes Häberle of the Children’s Research Center at the University Hospital Zurich’s University, “The chaperones guarantee that the enzyme molecules are folded appropriately and that the enzyme is correctly prepared for its usage or reset after use.” In order to learn more about the OTC deficit and, of course, prospective remedies, the novel test model is currently being utilized to evaluate OTC chaperones. “”

Dr. Damian Jacob Sendler and his media team provided the content for this article.

Damian Jacob Markiewicz Sendler

Damien Sendler

Sendler Damian

Dr. Sendler